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Weight-Bearing Exercise : Regular physical activity, particularly weight-bearing and resistance exercises, provides mechanical stimulus essential for bone maintenance

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have demonstrated the salutary cardioprotective effects of GLP-1 RAs following acute myocardial infarction 37

Over time, the central nervous system itself becomes sensitized

This pentapeptide is analogous to enkephalin, an endogenous opioid that functions as neurotransmitter and neuromodulator in both the central and peripheral nervous systems to regulate different physiological processes like pain, mood, and reward behaviors (Stefanucci et al., 2017)