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During the trial, additional anti-diabetic medication was initiated as an add on to randomized treatment by 7.7%, 3.2% and 3.5% of patients randomized to placebo, liraglutide 1.8 mg and semaglutide tablets 14 mg respectively

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But the company withdrew its support after two patients developed severe fever and other toxic effects which halted human trials in a clinic in Breslau

Without intervention, roughly 25 to 40% of weight lost on GLP-1 medications comes from lean body mass rather than fat