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Spurred by recent development of materials science and nanotechnology, various strategies for regulation of BBB permeability were developed as well as a library of brain-targeted drug delivery systems

Streit WJ, Mrak RE, Griffin WST (2004) Microglia and neuroinflammation: a pathological perspective

The needle is bevel oriented to the safety cover to facilitate low-angle injections

In tumor cells, where intracellular GSH levels are often elevated, this reductive environment may facilitate metal-catalyzed redox cycling and paradoxically intensify oxidative stress

and plays a role in inflammatory cell adherence, anticoagulation, and angiogenesis