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It regulates: Satiety signaling Insulin secretion Gastric emptying Postprandial glucose response Energy partitioning This is why the idea that the microbiome controls appetite is better understood as microbiome-influenced appetite signaling, where microbial metabolites may help shape satiety, gastric emptying, and metabolic response

Potential Benefits Increases in lean body mass and reductions in adipose tissue in clinical studies [7] [8]

3 In separate clinical studies of adults with overweight or obesity, about 1 in 4 taking Wegovy oral semaglutide 25 mg (64 weeks) and about 1 in 3 taking Wegovy injection 2.4 mg (68 weeks) lost 20% of body weight, alongside diet and exercise

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, Ahima, R