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Huang Y, et al

Conditions including acute hepatitis, cirrhosis, non-alcoholic fatty liver disease (NAFLD), and liver cancer have all been associated with elevated serum B12

For metabolic support specifically, hibiscus polyphenols have been shown to inhibit adipogenesis (the formation of new fat cells), promote lipolysis (the breakdown of fat), and modulate inflammatory pathways related to metabolic syndrome

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They reduce the formation of amyloid plaques in the brain, decrease the production of ROS and could be of interest in other situations such as: ischemia-reperfusion injury, atherosclerosis, diabetes, cancer, obesity, platelet aggregation, blood pressure, depigmentation and cardiomyocyte and cardiac hypertrophy (Thandapilly et al., 2011