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You do not know what is in them

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Additionally, if you're taking vitamin B12, some medicines can interfere with your ability to digest it, including: Aminosalicylic acid (Paser), used to treat digestive problems Colchicine (Colcrys, Mitigare, Gloperba) is an anti-inflammatory medicine used to prevent and treat gout Proton pump inhibitors (Prilosec, Prevacid) are used to reduce stomach acid Metformin (Glumetza, Fortamet, others), used to treat diabetes Vitamin C supplements QUESTION See Answer What are the warning signs of vitamin B12 deficiency

Sources: Pernicious Anemia: Definition, Symptoms, Causes & Treatment | Cleveland Clinic Pernicious Anemia - StatPearls | NCBI Bookshelf

These interactions are captured in the compatibility rules embedded within the TTDS