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If total caloric intake has dropped below 1,200 calories daily (for women) or 1,500 calories (for men), you are likely in too aggressive a deficit

Knowing that a slower pace is expected helps prevent strict diets or unhelpful changes that can make progress harder

GI tolerability pattern : MariTide's GI side effects appear concentrated at the first dose, while semaglutide's recur with dose escalation

however, its availability and use are restricted to research purposes unless prescribed by a licensed medical provider