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[9] Unopened vials of Bacteriostatic Water for Injection have a long shelf life, usually on the order of 2-3 years from the date of manufacture (check the expiration date on the vial)

10.1158/1535-7163.MCT-22-0490 227 WilsonK

[6] First-line pharmacological treatments include phosphodiesterase type 5 (PDE5) inhibitors, which are licensed, well-studied medications: Sildenafil (Viagra): Typically effective within 30-60 minutes, lasting 4-6 hours [7] Tadalafil (Cialis): Longer duration of action (up to 36 hours), also available as daily low-dose formulation [8] Vardenafil (Levitra): Similar efficacy to sildenafil with slightly different pharmacokinetics Avanafil (Spedra): Take approximately 30 minutes before sexual activity

Clin Gastroenterol Hepatol 2020

MAGEL2 was shown to modulate the stability and activity of key circadian regulators including CLOCK, BMAL1, and PER2 (Hirano et al., 2016