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Considering the prolonged half-life of most GLP-1 agonists currently prescribed, it is unfeasible to withhold these agents for weeks prior to surgery to achieve normalisation of gastric function with unknown impact on aspiration rates, appreciating the detrimental effects of poorer glycaemic control on withholding these agents and associated higher risk of peri/postoperative complications (major cardiovascular events, poor wound healing, increased wound infection etc.)

10.1016/j.atherosclerosis.2015.10.108 19 CraciunS.BalskusE

In comparison to the current models, the suggested model achieved the highest accuracy (94.75%) and recall (95.56%)

Test small topical patches before broader application

These typically resolve within hours to days and diminish with repeated doses