Reported side effects of corticosteroids include: Hydroelectrolytic disorders: sodium retention, potassium loss, hypokalemic alkalosis, fluid retention, congestive heart failure in susceptible patients, hypertension Musculoskeletal: muscle weakness, myopathy, loss of muscle mass, aggravation of myasthenic symptoms in myasthenia gravis, osteoporosis, vertebral compression fractures, aseptic necrosis of the head of the femur and humerus, pathologic fracture of long bones, tendon rupture Dermatological: impaired wound healing, atrophy and thinning of the skin, fragile skin, petechiae and ecchymoses, facial erythema, increased sweating, suppression of reactions to skin tests, allergic dermatitis, urticaria, and angioedema
[12] [13] [14] Local recurrence is Variable (5-40%) and perhaps greater than in normal schwannomas
Continual-G is made in Cypress, Texas at the INID labs
2019 systematic review places this human trial history in context alongside the broader musculoskeletal preclinical literature
if specific LCAC species (such as palmitoylcarnitine) are discussed this will be stated
