Produced in the liver, glutathione is involved in: Neutralizing free radicals Detoxifying heavy metals and toxins Supporting immune function Regenerating other antioxidants like vitamins C and E Maintaining mitochondrial (energy-producing) function In skin health, glutathione works in three main ways: Reduces oxidative stress that causes inflammation and cellular damage Supports liver detoxification, which helps clear toxins and hormones that may contribute to acne Modulates melanin production by influencing the enzyme tyrosinase, potentially reducing hyperpigmentation When combined with vitamin C, glutathione becomes even more effective
Gonzlez-Guerrero M, Oger E, Benabdellah K, Azcn-Aguilar C, Lanfranco L, Ferrol N (2010) Characterization of a CuZn superoxide dismutase gene in the arbuscular mycorrhizal fungus Glomus intraradices
It can, in fact, recycle antioxidants such as vitamins C and E14 that is, return them to antioxidant capacity even after they've neutralized a pro-oxidant further helping your body to keep its pro-oxidants and antioxidants in balance
The second one, is a human ecologic study proposing the hypothesis for a correlation between the glutathione S-transferase T1 (GSTT1) polymorphism and the outcome of COVID-19 (Saadat, 2020)
For instance, an increase in RO level is closely related to neuronal apoptosis, which impinges on the function and health of the nervous system, underscoring the need for further mechanistic studies [68]