This randomized, double-blind, placebo-controlled trial included 6,001 participants, with a mean baseline eGFR of 62 mL/min/1.73 m 2 , nearly half of whom had an eGFR below 60 mL/min/1.73 m 2
But for people with certain conditions, or those on certain medications, who are having difficulty meeting their weight goals through diet and exercise alone, metformin could provide an extra boost
As a trusted endocrinologist in Singapore, we emphasize that the decision to continue semaglutide despite menstrual irregularities depends heavily on individual circumstances
For example: Semaglutide + Tirzepatide Not recommended Semaglutide + Retatrutide Not recommended Tirzepatide + Retatrutide Not recommended Using multiple GLP-1 medications together may increase side effects without proven additional benefit
(Zepbound is a registered trademark of Eli Lilly, and Wegovy is a registered trademark of Novo Nordisk, and we claim no affiliation with or endorsement by either company.)
