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Timeline and Severity of Post-Meal Diarrhea During GLP-1 Therapy Clinical data from semaglutide trials shows that diarrhea typically begins within the first week or two of starting therapy or increasing doses, peaks around weeks 3 to 6, and improves significantly by weeks 8 to 12 as your digestive system adapts

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Slow titration will also help decrease gastrointestinal symptoms that may arise

Understanding how semaglutide works and its effects on the body can help you manage your health better and ensure you get the most benefit from your treatment

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