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KLOW's clearance profile is well-characterized, predictable, and manageable

Combining the therapeutic approaches of GLP-1 agonists (which target extrahepatic mechanisms for metabolic disorders) with resmetirom (which target intrahepatic mechanisms for MASH and liver fibrosis) seems like a promising strategy for addressing fat accumulation, inflammation, and fibrosis associated with MASH

Antioxidants (Basel) (2023) 12(5):1069