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It mimics the action of three hormones: GLP-1, GIP, and glucagon, which could further improve efficacy

Digestive side effects of GLP-1s include nausea, bloating, vomiting, constipation, diarrhea, belching, indigestion and more, outlined in Figure 3 of this article and Table 2 of this article

Among the four RCTs, three were rated as having some concerns and one as low risk, primarily due to potential selective reporting and deviations from intended interventions, whereas randomization and handling of missing data were generally at low risk

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