The relative contribution of each mechanism likely varies among individuals and may depend on baseline cardiovascular status, concurrent medications, and the specific GLP-1 receptor agonist used
The relationship between temperature and degradation follows Arrhenius kinetics, meaning that every 10-degree increase in temperature roughly doubles or triples the rate of chemical degradation
It's more like, physiologically, my body is telling me, You're actually hungry, instead of the emotional food noise I experienced pre-Mounjaro
GLP-1 released from diet & lifestyle strategies vs GLP-1 from medications The key difference to note is that the GLP-1 released via diet and lifestyle strategies stays active in the blood for significantly less time than the GLP-1 released via medications
In summary, antiamyloid mAbs have an irreplaceable advantage in clearing existing deposits and are a synergistic and complementary approach to current treatments for ATTR-CM