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Analyses of TfR1 expression and -H2AX nuclear foci quantification were performed using nonparametric MannWhitney test

Irritability

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Both genetic ablation and chemical inhibition of TRF1 telomeric localisation can block the growth of p53-null K-Ras G12V -induced lung carcinomas and PDGFA/B-induced glioblastomas in a telomere-length independent manner, remarkably without affecting mouse survival or tissue function 1,2,3

As a result, it may provide benefits for individuals with brain disorders and memory loss