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This hypothesis is supported by post-mortem evidence of reduced pyruvate dehydrogenase activity in the brains of individuals with ASD ( Alongside impairments in carbohydrate metabolism, evidence of reduced carnitine levels suggest a dysfunction in mitochondrial -oxidation, leading to accumulation of long-chain fatty acids and elevated markers of lipid elongation and desaturation (Pastural et al., 2009)

1. Enrol (Cinnamon + Chromium Picolinate)

Nutrients 14:628

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doi:10.1093/ajcn/nqac240 Jungert A, McNulty H, Hoey L, et al