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GLP-1 is a hormone that tells your brain you are full and slows down the speed at which your stomach empties

Resident as well as infiltrated macrophages can be subject to macrophage polarization and adopt an M1 pro-inflammatory phenotype associated with increased inflammatory signalling or an M2 anti-inflammatory phenotype associated with the resolution of the inflammatory process by producing anti-inflammatory cytokines

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In terms of hepatotoxicity, metabolic activation of acetaminophen is much lower in the Africans than Caucasians [112], and the rate of acetaminophen-induced hepatotoxicity is low in Asian populations as compared with patients from Western countries [113]