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Semaglutide injections act on pathways that regulate appetite and glucose control

whilst many people experience improved confidence and body image with weight loss, others may find the transition challenging or experience relationship dynamics shifts that affect intimacy

Estrogen deficiency can also impact appetite regulation, according to animal studies that have linked decreased estrogen with increased hunger and a reduction in spontaneous physical activity

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These symptoms often lessen over time, but some people find them persistent enough to require dose adjustments or temporary pauses