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NCT01930188

The near-zero hypoglycemia rate (0.6% of participants) directly confirmed the glucose-dependent nature of the insulin secretory mechanism in a clinical population

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If solution storage is necessary, researchers commonly use sterile buffers around pH 56, aliquot to reduce freezethaw exposure, and store refrigerated shortterm (often referenced as up to ~30 days at ~4C (39F) as general guidance), freezing when not in use depending on the protocol