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Beyond weight: the indications race What should drug discovery watch in the GLP-1 pipeline

This is due to several factors, including diet, hydration levels, and overall health

While most cases occur on sun-exposed skin (as shown in image 1), amelanotic melanomas can also arise on acral sites such as palms, soles and nail beds, or on mucosal surfaces, making them even more difficult to recognise

In the STEP TEENS trial, once-weekly semaglutide resulted in approximately 16% mean body weight reduction over 68 weeks, while liraglutide produced more modest reductions

However, clinical evidence tells a more nuanced story