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The review concludes, among other things, that betaine can lower homocysteine but can increase total cholesterol and LDL cholesterol at higher dosages

While Epithalamin showed a favorable safety profile in Russian clinical trials, Epithalon remains classified as a research compound

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Examination of statistical heterogeneity showed low heterogeneity overall (I 2 = 34%) and no heterogeneity between diagnostic subgroups (I 2 = 0%) (Figure 4)

These results are consistent with changes reported for human lenses during normal aging and cataract formation [107,108] suggesting that vitamin C oxidation plays a role in human lens aging and cataract