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Risks: gastrointestinal (GI) side effects, dehydration (which may contribute to kidney injury and orthostatic hypotension), sarcopenia , and osteoporosis

While the compound accumulates over time and produces effects regardless of timing, the pre-workout dose may provide subjective benefits during the session

Mitochondrial dynamics and metabolic regulation

Examples of approaches include conjugation to peptide carriers (e.g., to polylactic-co-glycolic acid [PLGA])