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Among the possible mechanisms underlying DDIs, those related to delayed gastric emptying have been most extensively studied
Author Contributions Conceptualization, E.N., S.G.-M., A.M
The syndrome has the distinction of being the first genetic disorder discovered to be caused by genomic imprinting, where the action of a gene depends on which parent the affected gene came from
These early changes tend to be subtle, such as reduced gut resilience or low-grade inflammation, long before obvious symptoms appear
At these concentrations, the GLP-1 receptor activation is sufficient to engage anti-inflammatory pathways without triggering the gastrointestinal side effects that make full-dose therapy difficult for many patients
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