glycine nac and glutathione Our Science – Nacuity Pharmaceuticals GlyNAC Supplementation Improves Glutathione Deficiency,

By enhancing glutathione levels, one could potentially mitigate oxidative stress, but there is a nuanced balance

Overexpression of GPx1 has the opposite effect, decreasing the expression of the adhesion molecules [6, 84]

doi: 10.1007/s12264-016-0067-0 Pubmed Abstract CrossRef Google Scholar View reference in article 86 HoaneMRWolyniakJGAkstulewiczSL

doi: 10.3389/fnut.2024.1399888 426 ZoiVKyritsisAPGalaniVLazariDSiokaCVoulgarisSet al

In the context of AD, fisetin has been shown to modulate inflammatory pathways and maintain cognitive function in AD transgenic mice (53) and to enhance memory and induce hippocampal long-term potentiation in rats (54)