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Modern incretin-based therapy still relies heavily on appetite suppression, but the addition of glucagon receptor activation may shift the model toward a broader metabolic strategy: reducing food intake while increasing energy expenditure and improving hepatic lipid metabolism

For a much deeper dive, including OTC medication options and when to seek more help, check out our GLP-1 Side Effects 101 guide

Approved for type 2 diabetes under the brand name Ozempic in 2017 and for chronic weight management as Wegovy in 2021, Semaglutide is administered weekly, offering a more convenient option compared to daily injections

But if it would be evidence only, I feel that first line therapy would be semaglutide only

LiPo batteries are capable of catching fire if not used properly - they are much more delicate than the older NiMH/NiCd batteries