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One consistent finding is that peak tissue changes often lag weight loss, with maximal soft-tissue sagging commonly observed 6 to 12 months post-initial weight loss, aligning with clinical guidance that peak GLP-1 weight loss occurs at about 52 weeks

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The legislation follows a CBS Philadelphia investigation that found nitrous oxide products, commonly known as whippets or laughing gas, being sold openly in smoke shops across multiple Pennsylvania counties

This can make the medication stay in the body for a longer time, leading to a longer-lasting effect

Studies suggest that long-term use can help maintain weight loss and contribute to better overall health