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Extending your time on a lower dose by 2-4 extra weeks is a common and effective strategy to improve long-term tolerance

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OBrien K, Hussain N, Warady BA, Kleiner DE, Kleta R, Bernardini I, Heller T, Gahl WA (2006) Nodular regenerative hyperplasia and severe portal hypertension in cystinosis

Consumers can also expect that each batch is rigorously tested and comes with a Certificate of Analysis (CoA) for full transparency

Open question Whether the same mechanisms are clinically meaningful in humans is not yet established