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Low-protein diets and supplementation with betaine, choline, folic acid, and vitamins B6 and B12 are standard therapies for older infants and children with CBS deficiency.12 MTHFR The MTHFR enzyme controls the conversion of inactive folate (5,10-methylenetetrahydrofolate) to active folate, 5-MTHF

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The PCR program was set as: 98 C for 3 min, 98 C for 10 s, 5560 C (temperature and time were set according to primers), 72 C for 30 s, and a total of 35 cycles