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It lowers the risk of dehydration and pancreatitis
When to speak to your GP Contact your GP if you experience: Increased thirst, frequent urination, or unexplained weight loss (possible signs of progression to diabetes) Persistent nausea or vomiting on Wegovy that prevents you from keeping fluids down Signs of dehydration (dark urine, dizziness, reduced urination) New or worsening vision changes Tingling or numbness in your hands or feet Feelings of anxiety, low mood, or being overwhelmed by managing your condition Ask your GP about: Referral to the NHS Diabetes Prevention Programme if you havent been offered it Your next HbA1c check (usually annually in primary care) Eligibility for specialist weight management services Frequently asked questions Can prediabetes be reversed without medication
Weight-Loss Results Need Careful Interpretation Retatrutide may produce larger average weight-loss signals than semaglutide in some trial settings, but that does not prove it is better for every person
Each approach has different evidence levels, timelines, and side effect profiles understanding the mechanisms helps in evaluating which compounds have the strongest research support for specific fat loss goals