In mouse models, the team introduced combined therapy including PD-L1 blocker and cyst(e) inase (a bioengineered enzyme that degrades cystine and cysteine) and such treatment can enhance the efficacy of CTL-mediated anticancer effects, supporting the idea that inducing ferroptosis could be considered a productive way for treating cancer and overcoming immunotherapy resistance ( Merkel cell carcinoma (MCC) is a rare, malignant neuroendocrine cutaneous tumor ( Artemisia annua ( Drug resistance Cell dedifferentiation is one of the signs of tumor progression and promotes resistance to current therapies ( As mentioned above, erastin can directly bind to VDAC2/3 and cause ferroptosis
An interesting case study of treatment-resistant mania showed an underlying case of neurodegeneration with iron brain accumulation (NBIA), proposing a potential association of resistant mania with iron accumulation [123]
References Federation, I.D
NEOVA's patented Copper Peptide Complex was developed specifically to close the gap between what GHK-Cu can do in research and what it actually does on skin
Squeeze a small amount of facewash on your wet palms, rub it gently to create a lather, and apply the product in a circular motion on your face and neck
