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The parent protein was first isolated in the 1990s by a Croatian research group led by Dionis Sikiric, who would go on to publish the majority of foundational BPC-157 studies

Cells characterized by rapid division (epithelial cells, bone marrow, myeloid cells) appear to have the greatest requirement for methylcobalamin

It usually occurs due to hormonal changes during pregnancy or due to use of oral contraceptives, or as a side effect of hormone replacement therapy

Wernicke syndrome and Korsakoff syndrome are related disorders that often occur with dry beriberi

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