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doi: 10.3748/wjg.v21.i29.8787 13 SimonECalinoiuLFMitreaLVodnarDC

As a general clinical principle: Retest HbA1c no sooner than three months after commencing B12 replacement therapy, and ideally once haematological recovery has been confirmed Confirm haematological recovery normalisation of MCV and haemoglobin before interpreting the repeat HbA1c as reliable Use interim glucose monitoring such as fasting plasma glucose, OGTT, or self-monitored blood glucose (SMBG) to assess glycaemic control during the treatment period

These results show that to reach a specific steady-state level of blood NAD + , different individuals required different dosages

Nausea occurred in 16-46% of patients depending on dose, diarrhea in 16-26%, and vomiting in 8-22%

individual sources vary