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Nitric oxide and mitochondrial biogenesis

The adjusted hazard ratio for nAMD in the exposed cohort was 2.21 (95% CI: 1.652.96), indicating more than double the risk

In vivo cognitive tests such as the Morris water maze and the passive step-down avoidance tests were performed with rats given oral doses of aqueous or 95% ethanolic extract of Schisandra chinensis (petroleum ether fraction) and showed that the extract could partially reverse the effects of decreasing activity of superoxide dismutase, catalase and the overall antioxidant effect induced by D-galactose, and to maintain normal levels of glutathione, malondialdehyde and nitric oxide in serum, prefrontal cortex, striatum, and hippocampus