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In other words, low doses might have some of the same positive impacts on weight management that standard doses have with women in perimenopause and menopause

However, the biological plausibility of risk, combined with the lack of long-term human data, demands caution

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Progress is often evaluated using several markers, including: Weight and body composition trends Blood sugar markers such as fasting glucose or HbA1c Side-effect tolerance during dose increases Strength and muscle preservation during weight loss When these indicators are moving in the right direction, treatment is usually progressing appropriately