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Nearly 40% of approved drugs and up to 90% of new chemical entities face this limitation, resulting in therapeutic inefficacy and costly clinical development

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Supports cellular energy production by assisting in the transport of fat into the mitochondria where it is oxidized and converted into ATP (chemical energy for the cell)

Both raw and FDR-adjusted p-values are reported in Supplementary Tables S2 and S4

Overexpression of a key enzyme in GSH biosynthesis resulted in higher steady-state levels of GSH and enhanced nickel, cobalt, zinc and to a lesser extent cadmium tolerance in A