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But, the authors of the review conclude that its effect may be even greater in these people

Because elderly patients are more likely to have decreased renal function, care should be taken in dose selection in the elderly based on renal function

IGF-1 LR3 produces more direct and faster anabolic signaling in skeletal muscle compared to growth hormone because it binds directly to IGF-1 receptors without requiring hepatic conversion or binding protein modulation