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Women may be particularly affected during hormonal transitions, such as menopause or postpartum periods

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With RSL3-induced reduction in pNPM1 levels, DNA damage sites (marked by -H2AX foci) were not repaired due to limited availability of pNPM1

Instead of targeting one single symptom, it coordinates multiple repair pathways at once

Optimal Timing: Taking with a meal containing healthy fats (eggs, nuts, avocado) enhances absorption of fat-soluble phytoceramides