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Fasting insulin and HOMA-IR (a measure of insulin resistance) decreased substantially at all active doses, with the greatest reductions at 8mg and 12mg

Approved Uses Semaglutide is approved for two main uses: managing type 2 diabetes and helping with weight loss

When the bad guys start to outnumber the good guys, it can affect everything from your weight to your hormones, and even contribute to chronic conditions like diabetes

Gastrointestinal side effects (nausea, vomiting, diarrhea, constipation) occur in 40 to 70% of patients during dose titration [4][6]

Stopping is the safest option and avoids continued exposure to a compound without clear benefit