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Avoid sodium azide when it may interfere with downstream applications, especially cell-based assays

The redox cycling enzymes thioredoxin, thioredoxin reductase, sulfiredoxin, peroxiredoxin, GSH peroxidase, superoxide dismutase 1, and catalase, and several GSH S-transferases, which are the enzymes mediating the elimination of ROS, are all Nrf2 targets (242)

The phase 2 trial demonstrated this clearly, with android visceral fat mass decreasing by up to 31.4% at the 12mg dose

Lifestyle modification including weight loss, regular physical activity, and a balanced diet remains the cornerstone of managing fatty liver disease, with no specific supplements currently recommended as standard treatment

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