Human GLP-1 was rapidly degraded by DPP-4, while EX showed prolonged kinetics because of its resistance to proteolysis of DPP-4 (48)
462 Inhibition of the NF-B signaling pathway leads to the decreased production of inflammatory mediators, including adhesion molecules and chemokines, which are crucial for the recruitment of immune cells to sites of inflammation
6,7 Importantly, Berberine may interact adversely with hypoglycemic medications, potentially causing excessive lowering of blood glucose levels, and it can also interact with antibiotics
Theres uncertainty around the effectiveness of microdosing compounded versions of GLP-1s and a lack of research on the safety of this method
Discussing options with a health care provider can help find better alternatives that align with the patients health goals, such as controlling appetite or improving metabolic health