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Catalysis within the lipid bilayer-structure and mechanism of the MAPEG family of integral membrane proteins

Once the adipose tissue expandability exceeded limit under overnutrition, excess lipids and toxic lipid metabolites (FFA, diacylglycerol, ceramide) accumulated in non-adipose tissues, thus leading to lipid-induced toxicity (lipotoxicity) and developed IR in liver and muscle

The acetyl-CoA can be used for protein acetylation or fatty acid synthesis

Neuronal effects of acute citalopram detected by pharmacoMRI

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