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doi: 10.1016/j.jri.2020.103248 102 TinoABChitcholtanKSykesPHGarrillA

Moreover, the findings that mice with neutrophil-specific Gpx4 haploinsufficiency recapitulate key clinical features of human SLE, including autoantibodies, neutropenia, skin lesions and proteinuria, and that the treatment with a specific ferroptosis inhibitor significantly ameliorates disease severity in lupus-prone mice reveal the role of neutrophil ferroptosis in lupus pathogenesis

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However, it's crucial to note that these findings don't mean all B vitamins are problematic

However, some people with a nitrous oxide-induced vitamin B12 deficiency may wake up with severe symptoms all at once