Research on GLP-1 receptor agonists shows that dose tolerance builds over 48 weeks, meaning a lower starting point does not compromise long-term resultsit simply extends the timeline and improves adherence
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N Engl J Med 377(13):12281239 Marso SP, Daniels GH, Brown-Frandsen K, Kristensen P, Mann JF, Nauck MA, Nissen SE, Pocock S, Poulter NR, Ravn LS, Steinberg WM, Stockner M, Zinman B, Bergenstal RM, Buse JB (2016) Liraglutide and cardiovascular outcomes in type 2 diabetes
We encourage maintaining a nourishing, high-protein diet, but most patients are able to lose weight without the need for uncomfortably restrictive dieting or calorie counting