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Measurable changes in fasting glucose and subjective energy typically appear within 710 days, while body composition shiftsreduced visceral adiposity and improved lean mass ratiobecome evident at 46 weeks with consistent dosing

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doi: 10.1007/s00125-007-0604-5 67 TajimaSIkedaYSawadaKYamanoNHorinouchiYKihiraYet al