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Lochman, P

Type 1 is the enzyme variant primarily responsible for converting testosterone to DHT in hair-damaging locations, and this inhibition occurs with greater specificity for the hair-relevant type 1 than the prostate-relevant type 2

All other agents discussed are investigational

In fed-batch fermentation, the #14 mutant achieved 1.98 g/L of glutathione using molasses and CSL as carbon and nitrogen sources, comparable to yields from expensive complex media containing peptone and yeast extract