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What side effects should I expect when using Wegovy or Mounjaro for PCOS-related weight loss

Mood Disorders Both glutamate overactivity and reduced GABAergic signaling are implicated in mood disorders such as depression and bipolar disorder

Twice-weekly glepaglutide significantly beat placebo at reducing patients parenteral support needs, though the once-weekly dosing regimen failed to achieve statistical significance

bDoses that are demonstrated to be statistically significantly superior to placebo

Figure 3 GLP-1RAs compared to placebo A total of six RCTs (674 belonged to the GLP-1RAs group and 670 to the placebo group) compared the change in HbA1c from baseline to follow-up in patients with T2DM ( 2 = 77%) ( Figure 4A )