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All participants followed strict dietary restrictions that included avoidance of spicy food and alcohol or the use of any odorized products a day before sample collection/session

PMID 9606808

However, Phase 2 trials are not always powered or designed to detect rare psychiatric adverse events, and longer-term Phase 3 data which would provide a more comprehensive safety profile had not been fully published at the time of writing

Whether that matters clinically depends on the patient: for a younger patient with muscle to spare, the trade-off may be acceptable

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