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Spironolactone tablets (25mg, 50mg, & 100mg), Rx only, has not been approved by the FDA as safe and effective to treat acne, however studies have shown that it may treat acne

However, its FDA-approved to treat type 2 diabetes in adults and children ages 10 and up, in combination with diet and exercise

In this Review, we summarize current preclinical and clinical evidence, showing that the riskbenefit profile of GLP1RAs remains favourable in individuals with T2DM and obesity, although caution is warranted in those with a low cardiometabolic risk, for whom the potential risks of cancer might outweigh any expected benefits

The exact instruction varies by practice and by patient risk, and it has to come from your surgical team, never from an article